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Outline of the acoustofluidic biosensor features and mechanisms of optical detections (immunofluorescence and SERS sensing). The device comprises a transparent piezoelectric lithium niobate (LiNbO3) substrate with patterned interdigital transducers (IDTs) and a square-shaped glass capillary bonded to the substrate. Surface acoustic waves concentrate particles at either the center or the perimeter of a glass capillary. Adapted with permission from [89]. Copyright 2020, Wiley-VCH.
