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. 2021 Apr 27;26(9):2554. doi: 10.3390/molecules26092554

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Microscopic view of control and fur keratin-derived powder containing casomorphin (FKDP-0.1%Caso)-treated wounds during the course of healing; hematoxylin-eosin. Original magnification: 100×. Legend: -epidermis; -hair follicle; -empty zones; -blood extravasation. (B) The effect of fur keratin-derived powder (FKDP) containing 0.1% casomorphin on skin wound healing. Because of the decreasing number of surviving mice, the data were only tested by the t-test for dependent samples (for each post-wounding day separately), with no prior two-way analysis of variance. Mice numbers at Day 5, N = 20; Day 8, N = 12; Day 15, N = 6. (C) Changes in cytokine level during wound healing in diabetic mice (p-value < 0.05 was considered significant, were * p-value < 0.05, ** p-value < 0.01, *** p-value < 0.001). (D) Changes in blood glucose level (BGL) during diabetes induction. (The data were statistically significant if p < 0.05 two-way analysis of variance, followed by Bonferroni post hoc tests, mean ± standard error of the mean) (color online, black and white in print).

Inline graphic — (A) Microscopic view of control and fur keratin-derived powder containing casomorphin (FKDP-0.1%Caso)-treated wounds during the course of healing; hematoxylin-eosin. Original magnification: 100×. Legend: -epidermis; -hair follicle; -empty zones; -blood extravasation. (B) The effect of fur keratin-derived powder (FKDP) containing 0.1% casomorphin on skin wound healing. Because of the decreasing number of surviving mice, the data were only tested by the t-test for dependent samples (for each post-wounding day separately), with no prior two-way analysis of variance. Mice numbers at Day 5, N = 20; Day 8, N = 12; Day 15, N = 6. (C) Changes in cytokine level during wound healing in diabetic mice (p-value < 0.05 was considered significant, were * p-value < 0.05, ** p-value < 0.01, *** p-value < 0.001). (D) Changes in blood glucose level (BGL) during diabetes induction. (The data were statistically significant if p < 0.05 two-way analysis of variance, followed by Bonferroni post hoc tests, mean ± standard error of the mean) (color online, black and white in print).