Table 2.
The effect of FKDP-casomorphin dressing on the epidermis and the time course of changes in the number of microhemorrhages in full-thickness surgical skin wounds in male C57BL/6J mice.
| Experiment Day (Number of Mice) | Wound Status | Epidermal Status |
Number of Micro-BloodExtravasations (mean ± SD) |
ANOVA Results |
|---|---|---|---|---|
| Day 5 (N = 3) |
Undressed | − | 16.56 ± 3.87 | Experimental day effect: F2.6 = 139.10 p = 0.001 Dressing effect: F1.6 = 0.65 p = 0.452 Interaction effect (Dressing × Experiment Day) F2.6 = 1.81 p = 0.242 |
| Dressed | − | 19.00 ± 2.19 | ||
| Day 8 (N = 3) |
Undressed | + | 14.39 ± 2.10 | |
| Dressed | + | 11.17 ± 1.86 | ||
| Day 15 (N = 3) |
Undressed | + | 6.39 ± 0.84 | |
| Dressed | ++ | 4.00 ± 0.33 **,# |
**-p < 0.01 relative to the corresponding value for a dressed wound on day 5, 8, #-p < 0.05 relative to the corresponding value for the control wound; Abbreviations: −: ANOVA: analysis of variance; no visible epidermis; +: thin epidermis covering most of the wound; ++: epidermis of increased thickness covering the entire wound.