Figure 11.
(A) Schematic illustration of the synthesis process for the versatile RGD-CCmMC/DOX nanovehicles; (B) schematic illustration of the therapeutic mechanism of the RGD-CCmMC/DOX nanoplatforms to enhance the overall anticancer efficiency of triple-combination photodynamic/photothermal/chemo-therapy in a solid tumor; (C) CLSM images of 4T1 cells treated with different formulations under laser irradiation. The production of intracellular ROS and O2 generation were measured by the green fluorescence intensity of DCF; (D) fluorescence microscopy images of 4T1 cells with various treatments using Calcein AM/PI staining, adapted with permission from [175].