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. 2021 May 5;22(9):4902. doi: 10.3390/ijms22094902

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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TGFβ3 is found throughout the ovarian stroma, within the follicles and around blood vessels. (A) Tissue section with specific staining throughout the stroma and around key structures in the ovary. (B) IgG negative control; (C) primordial follicles (asterisks); (D) blood vessels (arrowheads); (E) dense stroma. Panels (A,B) are representative histological sections performed in n = 6 patients, and (C–E) are cores from the TMA with representative images shown. Arrowheads: blood vessels, ta: tunica albuginea, c: cortex, m: medulla, asterisk: primordial follicles. (A,B) Scale bar = 400 µm; (C,D) scale bar = 100 µm.