Table 8.

The functional analysis of the downregulated genes at 12 h after LLL irradiation.

Gene Ontology (GO) ID and Terms on Biological Process (BP)	Count	%	p-Value
GO:0034645~cellular macromolecule biosynthetic process	102	23.83	6.82 × 10−2
GO:0051171~regulation of nitrogen compound metabolic process	94	21.96	2.85 × 10−2
GO:0010556~regulation of macromolecule biosynthetic process	90	21.03	1.75 × 10−2
GO:0010468~regulation of gene expression	90	21.03	6.33 × 10−2
GO:0018130~heterocycle biosynthetic process	90	21.03	8.55 × 10−2
GO:0034654~nucleobase-containing compound biosynthetic process	89	20.79	8.55 × 10−2
GO:0019219~regulation of nucleobase-containing compound metabolic process	88	20.56	3.19 × 10−2
GO:2000112~regulation of cellular macromolecule biosynthetic process	87	20.33	2.26 × 10−2
GO:0097659~nucleic acid-templated transcription	82	19.16	2.93 × 10−2
GO:0032774~RNA biosynthetic process	82	19.16	6.02 × 10−2
GO:0051252~regulation of RNA metabolic process	81	18.93	3.76 × 10−2
GO:0006351~transcription, DNA-templated	80	18.69	2.03 × 10−2
GO:1903506~regulation of nucleic acid-templated transcription	80	18.69	2.30 × 10−2
GO:2001141~regulation of RNA biosynthetic process	80	18.69	2.58 × 10−2
GO:0006355~regulation of transcription, DNA-templated	79	18.46	2.76 × 10−2
GO:0023051~regulation of signaling	77	17.99	1.04 × 10−3
GO:0010646~regulation of cell communication	76	17.76	1.04 × 10−3
GO:0009966~regulation of signal transduction	71	16.59	6.57 × 10−4
GO:0065009~regulation of molecular function	71	16.59	2.42 × 10−3
GO:0035556~intracellular signal transduction	69	16.12	8.62 × 10−4
GO:0009893~positive regulation of metabolic process	68	15.89	3.21 × 10−2
GO:0010604~positive regulation of macromolecule metabolic process	67	15.65	1.20 × 10−2
GO:0006796~phosphate-containing compound metabolic process	67	15.65	5.25 × 10−2
GO:0006793~phosphorus metabolic process	67	15.65	5.42 × 10−2
GO:0031325~positive regulation of cellular metabolic process	66	15.42	1.53 × 10−2
GO:0044085~cellular component biogenesis	65	15.19	3.58 × 10−2
GO:0050790~regulation of catalytic activity	63	14.72	7.74 × 10−4
GO:0022607~cellular component assembly	63	14.72	9.06 × 10−3
GO:0007166~cell surface receptor signaling pathway	59	13.79	5.38 × 10−2
GO:0051128~regulation of cellular component organization	57	13.32	9.42 × 10−3
GO:0016310~phosphorylation	56	13.08	6.37 × 10−3
GO:0051246~regulation of protein metabolic process	55	12.85	7.26 × 10−2
GO:0033554~cellular response to stress	53	12.38	1.80 × 10−4
GO:0007399~nervous system development	52	12.15	2.06 × 10−2
GO:0031324~negative regulation of cellular metabolic process	52	12.15	6.82 × 10−2
GO:0032268~regulation of cellular protein metabolic process	51	11.92	9.24 × 10−2
GO:1902531~regulation of intracellular signal transduction	50	11.68	5.12 × 10−4
GO:0044093~positive regulation of molecular function	50	11.68	2.35 × 10−3
GO:0006928~movement of cell or subcellular component	48	11.21	4.02 × 10−3
GO:0009605~response to external stimulus	47	10.98	6.26 × 10−2
GO:0043085~positive regulation of catalytic activity	46	10.75	7.29 × 10−4
GO:0007049~cell cycle	46	10.75	2.94 × 10−3
GO:0006357~regulation of transcription from RNA polymerase II promoter	46	10.75	1.51 × 10−2
GO:1902589~single-organism organelle organization	45	10.51	2.52 × 10−3
GO:0006366~transcription from RNA polymerase II promoter	45	10.51	2.03 × 10−2
GO:0008219~cell death	44	10.28	8.02 × 10−2
GO:0031399~regulation of protein modification process	43	10.05	1.20 × 10−2
GO:0048585~negative regulation of response to stimulus	41	9.58	1.17 × 10−3
GO:0007155~cell adhesion	41	9.58	3.80 × 10−2
GO:0022610~biological adhesion	41	9.58	3.98 × 10−2

Count: genes involved in the term; percentage (%): involved genes/total genes; p-value: modified Fisher exact p-value.