Table 1.
Phthalate diesters and their respective metabolites detected in maternal serum during pregnancy, and sums of metabolites used for statistical analysis.
| Phthalate Diester | Abbreviation | Human Serum Metabolite | Abbreviation |
|---|---|---|---|
| Di-methyl phthalate | DMP | Mono-methyl phthalate | MMP a |
| Di-ethyl phthalate | DEP | Mono-ethyl phthalate | MEP |
| Di-iso-propyl phthalate | DiPrP | Mono-(4-oxopentyl) phthalate | MiPrP a |
| DPrP | Mono-propyl phthalate | MPrP a | |
| Di-iso-butyl phthalate | DiBP | Mono-iso-butyl phthalate | MiBP |
| Di-n-butyl phthalate | DnBP | Mono-n-butyl phthalate | MnBP |
| Mono-(3-hydroxybutyl) phthalate | MHBP | ||
| Butylbenzyl phthalate | BBzP | Mono-benzyl phthalate | MBzP |
| Di-n-pentyl phthalate | DPP | Mono-n-pentyl phthalate | MPP a |
| Mono-(4-hydroxypentyl) phthalate | MHPP a | ||
| Di-(2-ethyl-hexyl) phthalate | DEHP | Mono-(2-ethyl-hexyl) phthalate | MEHP |
| Mono-(2-ethyl-5-hydroxyhexyl) phthalate | MEHHP a | ||
| Mono- (2-ethyl-5-oxohexyl) phthalate | MEOHP a | ||
| Mono-(2-ethyl-5-carboxypentyl) phthalate | MECPP | ||
| Mono-(2-carboxymethyl-hexyl) phthalate | MCMHP | ||
| Di-n-hexyl phthalate | DHxP | Mono-n-hexyl phthalate | MHxP a |
| Mono-(5-hydroxyhexyl) phthalate | MHHxP a | ||
| Mono-(5-carboxypentyl) phthalate | MCPeP a | ||
| Di-cyclohexyl phthalate | DCHP | Mono-cyclohexyl phthalate | MCHP a |
| Di-n-heptyl phthalate | DHpP | Mono-n-heptyl phthalate | MhepP a |
| Mono-(6-hydroxyheptyl) phthalate | MHHpP a | ||
| Mono-(6-carboxyhexyl) phthalate | MCHxP a | ||
| Di-octyl phthalate | DOP | Mono-octyl phthalate | MOP a |
| Mono-3-carboxypropyl phthalate | MCPP | ||
| Di-iso-nonyl phthalate | DiNP | Mono-iso-nonyl phthalate | MiNP |
| Mono-hydroxy-iso-nonyl phthalate | MHiNP a | ||
| Mono-oxo-iso-nonyl phthalate | MOiNP a | ||
| Mono-carboxy-iso-octyl phthalate | MCiOP | ||
| Di-iso-decylphthalate | DiDP | Mono-iso-decyl phthalate | MiDP |
| Mono-(9-hydroxydecyl) phthalate | MHiDP a | ||
| Mono-(9-oxodecyl) phthalate | MOiDP a | ||
| Mono-(9-carboxynonyl) phthalate | MCiNP a | ||
| Sums of phthalate metabolites | |||
| ΣMBP(i + n) | Sum of MiBP and MnBP in ng/mL | ||
| ∑DEHPmetab | Molar sum of MEHP, MCMHP, and MECPP expressed as DEHP in ng/mL | ||
| ∑DiNPmetab | Molar sum of MiNP and MCIOP expressed as DiNP in ng/mL | ||
| ∑DEHP + DiNPmetab | Molar sum of MEHP, MCMHP, MECPP, MiNP, MCiOP expressed as MEHP in ng/mL | ||
| ∑low MW phth.metab | Molar sum of MEP, MiBP, MnBP, and MHBP expressed as MEP in ng/mL | ||
| ∑high MW phth.metab | Molar sum of MBzP, MEHP, MCMHP, MECPP, MCPP, MiNP, MCiOP, and MiDP expressed as MEHP in ng/mL | ||
| ∑all phth.metab | Molar sum of MEP, MiBP, MnBP, MHBP, MBzP, MEHP, MCMHP, MECPP, MCPP, MiNP, MCiOP, and MiDP expressed as MEHP in ng/mL | ||
a The proportion of samples greater than the limit of detection were not sufficient for inclusion in the analysis.