Table 2.
Prognostic variables in patients undergoing hepatic resection.
| Variables | Overall Survival | Recurrence | ||||
|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | |||
| p | HR (95% CI) | p | p | HR (95% CI) | p | |
| Male sex | 0.423 | 0.694 | ||||
| Age > 60 years | 0.319 | 0.047 | 5.07 (1.67−15.15) | 0.004 | ||
| Cause of liver disease | 0.133 | 0.144 | ||||
| AST > 90 U/L | 0.353 | 0.473 | ||||
| ALT > 60 U/L | 0.357 | 0.595 | ||||
| Child−Pugh class B/C | 0.095 | 1.02 (0.94−1.09) | 0.616 | 0.120 | ||
| Tumor size > 5 cm | <0.001 | 7.97 (3.13−20.24) | <0.001 | <0.001 | 1.81 (0.63−5.18) | 0.263 |
| Tumor multiplicity | 0.075 | 1.56 (0.43−5.65) | 0.491 | 0.019 | 1.85 (0.44−7.71) | 0.398 |
| α-fetoprotein | 0.317 | <0.001 | 1.54 (0.56−4.23) | 0.396 | ||
| Tumor stage (mUICC) | <0.001 | 2.46 (1.45−4.16) | 0.001 | <0.001 | 2.71 (1.48−4.96) | 0.001 |
| TERT promoter mutation | 0.029 | 4.24 (1.75−10.26) | 0.001 | 0.162 | 2.98 (1.01−8.33) | 0.048 |
| TERT expression | 0.913 | 0.362 | ||||
| Telomere length | 0.446 | 0.208 | ||||
HR, hazard ratio; CI, confidence interval; HBV, hepatitis B virus; HCV, hepatitis C virus; AST, aspartate aminotransferase; ALT, alanine aminotransferase; mUICC, modified Union for International Cancer Control; TERT, telomerase reverse transcriptase.