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. 2021 Apr 28;22(9):4673. doi: 10.3390/ijms22094673

Figure 2.

Figure 2

Illustration of common metastatic sites in breast cancer [2]. The most common metastatic sites for breast cancer are the bones, axillary lymph nodes, liver, and lungs. Approximately 10–40% of breast cancer tumors have metastasized in the internal mammary gland. Breast cancer can advance to distant metastatic sites depending on the molecular subtype; for example, Luminal A, B, HER2+, triple negative breast cancer (TNBC), or basal-like breast cancer. Locoregional lymphatic spread is sparse in TNBC compared to other subtypes, while brain metastases are more frequent in TNBC compared to luminal tumors [2].