AJCC	American Joint Committee on Cancer
ASCO	American Society of Clinical Oncology
bTMB	Blood tumor mutational burden
CI	Confidence interval
CPS	Combined positive score.
CTLA4	Cytotoxic T lymphocyte Antigen 4
DFS	Disease free survival
EMA	European Medicines Agency
FDA	Food and Drug Administration
HNSCC	Head and neck squamous cell carcinoma
HPV	Human papilloma virus
HR	Hazard ratio
IC	Investigators choice
IHC	Immunohistochemical staining
IS	Immunoscore
ISH	In situ hybridization
Mb	Megabase
NCI	National Cancer Institute
NGS	Next generation sequencing
OPSCC	Oropharyngeal squamous cell carcinoma
OS	Overall survival
PCR	Polymerase chain reaction
PD-1	Programmed Cell Death Protein 1
PD-L1	Programmed death ligand-1
RSI	Radiosensitivity Index
SOC	Standard of car
TILs	Tumor infiltrating lymphocytes
TMB	Tumor mutational burden
TME	Tumor microenvironment
TNM	Tumor, node, metastasis
TPS	Tumor proportion score
Tregs	Regulatory T-cells
UICC	Union for International Cancer Control
US	United States