Table 1.

microRNAs involved in cardiac remodeling.

MicroRNA	Sample	Model	Sex	Effect on Expression	Target	Reference
miR-101	Sprague–Dawley rats	MI	Male and female	Decreases	RUNX1	[17]
miR-132	miR-132 KO and WT mice	MI	Male	Decreases		[18]
miR-21	miR-21 KO and WT mice	MI	Male	Increases	KBTBD7	[19]
miR-145	miR-145 KO and WT mice	MI	Male	Decreases	KLF4	[20]
miR-26b	Mice	MI	Male	Decreases	PTGS2	[21]
miR-146	CTO patient plasma Mice Pigs	MI	Male and female	Increases	IRAK1CEACAM1	[22]
miR-22	Mice	MI	Male	Increases	Cav3	[23]
miR-330	Mice	MIRI	Male	Increases	SRY	[24]
miR-202	Sprague–Dawley rats	MIRI	Male	Decreases	TRPM6	[25]
miR-30e	Sprague–Dawley rats	MIRI	Male	Decreases	SOX9	[26]
miR-23a	Patient blood	MI	Male	Decreased	PTEN	[27]
miR-143	Patients	MI	Male and female	Increased	SPRY3	[28]
miR-124	Patient plasma Mice	MI		Increased	DHCR2	[29]
miR-19a/b	Patients Mice	MI	Male	Increased	SOCS1	[30]

Cav3, caveolin-3; CEACAM1, carcinoembryonic antigen-related cell adhesion molecule 1; CTO, chronic total occlusion; DHCR2, 3β-hydroxysteroid-delta24 reductase; IRAK1, interleukin 1 receptor associated kinase 1; KBTBD7, kelch repeat and BTB (POZ) domain containing 7; KLF4, Krueppel-like factor 4; KO, knockout; MIRI, myocardial ischemia–reperfusion injury; PTEN, phosphatase and tensin homolog; PTGS2, prostaglandin endoperoxide synthase 2; RUNX1, runt-related transcription factor 1; SOCS1, suppressor of cytokine signaling 1; SOX9, SRY-related high mobility group-box gene 9; SPRY3, sprouty3; SRY, sex-determining region Y; TRPM6, transient receptor potential cation channel, subfamily M, member 6; WT, wildtype.