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CD8+ lymphocytes in OSCC. (A) Numerous CD8+ cells (more than 106 cells/high power field) within the inflammatory infiltrate bordering the tumor invasion front; (B) Few CD8+ cells (less than 106 cells/high power field) within the invasion front; (C) Numerous CD8+ cells (more than 106 cells/high power field) within the intratumor inflammatory infiltrate; (D) Scattered isolated CD8+ cells (less than 24 cells/high power field) within the tumor. CD8 × 400.
