Relative Fatality Rate	Mixing Fraction	Large Tumours Metastases Detection Probability	Large Tumours Fatality Rate	True RR	Approximate HR
0.5	0.5	0.1333	0.6707	0.7761	0.6617
0.6	0.5	0.1500	0.6363	0.7271	0.6141
0.7	0.5	0.1647	0.6035	0.6981	0.5913
0.4	0.5	0.1143	0.7061	0.8599	0.7631
0.3	0.5	0.0923	0.7416	1.0138	1.0298
0.5	0.6	0.1429	0.6294	0.7719	0.6701
0.6	0.6	0.1579	0.6064	0.7249	0.6210
0.7	0.6	0.1707	0.5831	0.6971	0.5962
0.4	0.6	0.1250	0.6513	0.8524	0.7689
0.3	0.6	0.1034	0.6708	1.0001	1.0001
0.5	0.7	0.1538	0.5941	0.7593	0.6652
0.6	0.7	0.1667	0.5798	0.7182	0.6211
0.7	0.7	0.1772	0.5644	0.6938	0.5980
0.4	0.7	0.1379	0.6064	0.8297	0.7502
0.3	0.7	0.1176	0.6152	0.9589	0.9334
0.5	0.4	0.1250	0.7193	0.7719	0.6377
0.6	0.4	0.1429	0.6702	0.7249	0.5996
0.7	0.4	0.1591	0.6258	0.6971	0.5830
0.4	0.4	0.1053	0.7735	0.8524	0.7252
0.3	0.4	0.0833	0.8328	1.0001	1.0002
0.5	0.3	0.1176	0.7769	0.7593	0.5941
0.6	0.3	0.1364	0.7087	0.7182	0.5767
0.7	0.3	0.1538	0.6502	0.6938	0.5711
0.4	0.3	0.0976	0.8573	0.8297	0.6382
0.3	0.3	0.0759	0.9529	0.9589	0.8022
Parameter	Large	Small	RR	95% CI or Range	HR	95% CI or Range
No. of Cancers	332	44
Number with fup > 5 years	147	33
Number of deaths ≤ 5 years	165	10
5-year fatality rate	0.52	0.23
5-year survival	0.48	0.77	0.45	0.26–0.8	0.44	0.3–0.58
after Lead Time Bias correction
5-year fatality rate	0.52	0.35
5-year survival	0.48	0.65	0.69	0.45–1.05	0.67	0.53–0.81
after Length Time Bias correction
5-year fatality rate	0.52	0.40
5-year survival	0.48	0.60	0.78	0.69–1.01	0.64	0.57–1.03