A1-AT	α1-antitrypsin
ADAM	A disintegrin and a metalloprotease
AEC	Airway epithelial cell
AMP	Antimicrobial peptide
ASL	Airway surface liquid
βENaC-Tg	Transgenic mouse overexpressing the β-subunit of epithelial sodium channel
cAMP	Cyclic adenosine monophosphate
CAP	Channel-activating protease
CBF	Ciliary beat frequency
CF	Cystic fibrosis
CFTR	Cystic fibrosis transmembrane conductance regulator
CLD	Chronic lung disease
COPD	Chronic obstructive pulmonary disease
CTSB	Cathepsin B
CTSS	Cathepsin S
DNA	Deoxyribonucleic acid
ECM	Extracellular matrix
EGFR	Epidermal growth factor receptor
Egr	Early growth response
ENaC	Epithelial sodium channel
ERK	Extracellular receptor kinase
FRET	Fluorescence resonance energy transfer
HAT	Human airway trypsin-like protease
ICAM	Intercellular adhesion molecule
IMP	Investigational medical product
JNK	c-Jun N-terminal kinase
MARCKS	Myristoylated alanine-rich C kinase substrate
MCC	Mucociliary clearance
MMP	Matrix metalloprotease
mRNA	Messenger ribonucleic acid
NE	Neutrophil elastase
NET	Neutrophil extracellular trap
NF-κB	Nuclear factor κB
NSP	Neutrophil serine protease
PAR	Protease-activated receptor
PCD	Primary ciliary dyskinesia
PK	Pharmacokinetic
PKC	Protein kinase C
PGF	Placental growth factor
SLPI	Secretory leukocyte protease inhibitor
TIMP	Tissue inhibitor of metalloproteinases
TLR	Toll-like receptor
TMPRSS	Transmembrane protease, serine
TNF	Tumour necrosis factor