Table 2.
Predicted ADMET descriptors for the tested isoflavonoids and remdesivir.
| Compound | BBB Level a | Absorption Level b | PPB c | Solubility Level d |
|---|---|---|---|---|
| 1 | 3 | 0 | 2 | 3 |
| 2 | 2 | 0 | 2 | 3 |
| 3 | 3 | 0 | 1 | 3 |
| 4 | 2 | 0 | 0 | 3 |
| 5 | 2 | 0 | 2 | 3 |
| 6 | 1 | 0 | 0 | 2 |
| 7 | 2 | 0 | 0 | 2 |
| 8 | 2 | 0 | 1 | 3 |
| 9 | 2 | 0 | 2 | 3 |
| 10 | 1 | 0 | 2 | 2 |
| 11 | 2 | 0 | 0 | 2 |
| 12 | 4 | 2 | 0 | 4 |
| 13 | 3 | 0 | 1 | 3 |
| 14 | 3 | 0 | 2 | 3 |
| 15 | 3 | 0 | 2 | 3 |
| 16 | 3 | 0 | 1 | 3 |
| 17 | 3 | 0 | 1 | 3 |
| 18 | 3 | 0 | 2 | 3 |
| 19 | 2 | 0 | 2 | 2 |
| 20 | 2 | 0 | 1 | 2 |
| 21 | 3 | 0 | 1 | 3 |
| 22 | 3 | 0 | 1 | 3 |
| 23 | 2 | 0 | 2 | 2 |
| 24 | 3 | 0 | 2 | 3 |
| 25 | 3 | 0 | 2 | 3 |
| 26 | 2 | 0 | 2 | 3 |
| 27 | 1 | 0 | 2 | 2 |
| 28 | 4 | 1 | 2 | 2 |
| 29 | 4 | 1 | 2 | 1 |
| 30 | 4 | 1 | 2 | 2 |
| 31 | 4 | 1 | 2 | 2 |
| 32 | 2 | 0 | 0 | 2 |
| 33 | 4 | 1 | 1 | 2 |
| 34 | 4 | 1 | 0 | 2 |
| 35 | 4 | 1 | 0 | 2 |
| 36 | 4 | 0 | 1 | 3 |
| 37 | 4 | 2 | 2 | 2 |
| 38 | 4 | 0 | 0 | 2 |
| 39 | 3 | 0 | 1 | 3 |
| 40 | 3 | 0 | 1 | 3 |
| 41 | 3 | 0 | 2 | 3 |
| 42 | 3 | 0 | 2 | 3 |
| 43 | 3 | 0 | 0 | 3 |
| 44 | 3 | 0 | 2 | 3 |
| 45 | 4 | 0 | 2 | 3 |
| 46 | 4 | 0 | 0 | 3 |
| 47 | 3 | 0 | 0 | 3 |
| 48 | 2 | 0 | 1 | 2 |
| 49 | 4 | 0 | 2 | 2 |
| 50 | 4 | 0 | 1 | 2 |
| 51 | 2 | 0 | 1 | 2 |
| 52 | 2 | 0 | 2 | 2 |
| 53 | 4 | 2 | 2 | 1 |
| 54 | 4 | 2 | 2 | 1 |
| 55 | 2 | 0 | 1 | 2 |
| 56 | 4 | 2 | 2 | 2 |
| 57 | 4 | 1 | 2 | 1 |
| 58 | 4 | 1 | 1 | 2 |
| 59 | 2 | 2 | 2 | |
| Remdesivir | 4 | 3 | 0 | 2 |
a BBB level, blood brain barrier level, 0 = very high, 1 = high, 2 = medium, 3 = low, 4 = very low. b Absorption level, 0 = good, 1 = moderate, 2 = poor, 3 = very poor. c PBB, plasma protein binding, 0 means less than 90%, 1 means more than 90%, 2 means more than 95%. d solubility level, 0 = extremely low, 1 = very low, 2 = low, 3 = good, 4 = optimal.