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. Author manuscript; available in PMC: 2022 Jan 13.
Published in final edited form as: J Am Chem Soc. 2020 Dec 22;143(1):80–84. doi: 10.1021/jacs.0c11226

Figure 2.

Figure 2.

Fungal nonanolide biosynthesis. (A) The dcs and homologous biosynthetic gene clusters. The % sequence identities are shown in parenthesis; (B) Proposed biosynthetic pathway of 1. (C) LC-MS analysis of metabolites produced from expression of dcs genes in A. nidulans. (D) Assaying activity of DcsB using small molecule thioesters.