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. Author manuscript; available in PMC: 2022 Jan 13.
Published in final edited form as: J Am Chem Soc. 2020 Dec 22;143(1):80–84. doi: 10.1021/jacs.0c11226

Figure 3.

Figure 3.

Assaying the substrate promiscuity of DcsB. (A) Analogs 4b-4e used to probe functional group requirements; (B) simple alcohol-terminated substrates 4f-4l. a Isolated yield; b The cyclized product was not formed and only substrate hydrolysis was observed; c Yield determined by GC-MS analysis. Reaction conditions: 1 mM substrate, 0.5 μM DcsB except for 2k in which 2.4 μM DcsB was used.