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Analysis of the drug interaction between PLX4032 and U18666 A in LM16 R cells 1.
| Variable | CI ² | |
|---|---|---|
| PLX4032 | 3 µM U18666A | 10 µM U18666A |
| 30 µM | 0.38 ± 0.15 | 0.30 ± 0.05 |
| 10 µM | 0.44 ± 0.10 | 0.41 ± 0.04 |
| 3 µM | 0.57 ± 0.18 | 0.67 ± 0.06 |
| 1 µM | 0.55 ± 0.02 | 0.79 ± 0.04 |
1, Cell sensitivity was assessed by cell growth inhibition assay. 2 Combination Index (CI) values show synergistic drug interaction. CI are the mean ± SE of three independent experiments.
