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. 2021 May 10;13(9):1531. doi: 10.3390/polym13091531

Table 6.

Kinetics of drug permeation (F1–F9).

Formulation	Kinetics
	Zero Order Kinetics		First Order Kinetics		Higuchi Kinetics		Baker Lonsdale Kinetics		Hixson–Crowell Kinetics		Kosermeyer–Peppas Kinetics
	R ²	K₀	R ²	K₀	R ²	K₀	R ²	K₀	R ²	K₀	R ²	K₀	n
F1	0.393	0.144	0.258	0.004	0.308	1.309	0.904	0.251	0.872	0.000	0.511	5.938	0.061
F2	0.456	0.157	0.297	0.004	0.369	1.291	0.909	0.240	0.939	0.001	0.634	5.717	0.084
F3	0.437	0.153	0.281	0.004	0.352	1.300	0.911	0.240	0.859	0.001	0.604	5.584	0.077
F4	0.391	0.143	0.256	0.004	0.323	1.312	0.908	0.239	0.978	0.000	0.844	5.579	0.073
F5	0.390	0.143	0.257	0.004	0.321	1.309	0.909	0.237	0.979	0.000	0.825	5.584	0.073
F6	0.471	0.159	0.308	0.004	0.403	1.285	0.908	0.232	0.970	0.001	0.844	5.997	0.104
F7	0.414	0.148	0.277	0.004	0.340	1.294	0.907	0.238	0.974	0.001	0.755	5.767	0.080
F8	0.392	0.141	0.234	0.004	0.331	1.367	0.913	0.255	0.938	0.000	0.84	5.046	0.068
F9	0.451	0.155	0.292	0.004	0.373	1.297	0.907	0.240	0.980	0.001	0.750	5.727	0.088