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BL, Baseline; PD, progressive disease; DC, disease control; TS, tumor shrinkage; DEC, decreased; INC, increased; SD, standard deviation; N, no; Y, yes. *Differences in the mean and median cytokine levels were tested using Student’s unpaired t-test and Mann-Whitney U-test, respectively. **Pattern of changes in serum factor levels between BL and day 21 or PD. p-Values <0.05 are shown in bold.
