Table 3.

Virucidal efficacy of 10 mg/mL astodrimer sodium against SARS-CoV-2 (2019-nCoV/USA-WA1/2020), measured by a reduction in mean infectious virus (Log₁₀ pfu/mL), at 96 h post-infection.

Viral Load (pfu/mL)	Virus:Astodrimer Incubation Time	Reduction vs. Virus Control (Log10 ± SD)	Reduction vs. Virus Control (%)
106	5 s	0.10 ± 0.20	20.567
	10 s	0.03 ± 0.06	7.388
	30 s	0.10 ± 0.10	20.567
	1 min	0.33 ± 0.12	53.584
	10 min	2.20 ± 0.10	99.369
	15 min	3.67 ± 0.23	99.979
105	5 s	0.33 ± 0.21	53.584
	10 s	0.23 ± 0.06	41.566
	30 s	0.30 ± 0.17	49.881
	1 min	0.47 ± 0.21	65.855
	10 min	3.70 ± 0.26	99.980
	15 min	4.60 ± 0.10	99.998
104	5 s	−0.13 ± 0.21	−35.936
	10 s	0.07 ± 0.29	14.230
	30 s	0.10 ± 0.10	20.567
	1 min	0.10 ± 0.00	20.567
	10 min	5.07 ± 0.25	>99.999
	15 min	5.83 ± 0.12	>99.999

Virus control = untreated virus, 0 mg/mL astodrimer sodium; SD = standard deviation.