Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 16;2021(2):hoab020. doi: 10.1093/hropen/hoab020

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 2. — Ageing regulation of anti- and pro-longevity genes in human oocyte transcriptomes. (A) Distributions of correlations of all genes (grey), GeneAge anti-longevity genes (orange) and GeneAge pro-longevity genes (blue) and their significant differences. Distributions were compared with an ANOVA, and the Tukey Honest Significant Difference method was used to control for the Type I error rate across multiple comparisons. The 0.024 P value denotes a significant difference between how anti-longevity genes and pro-longevity genes associate with age, which is in opposing directions. The changes in direction are opposite to what would be required for a longevity benefit. (B) Selection of GeneAge anti- and pro-longevity genes that correlated with age in a manner opposite to what would be required for a longevity benefit. Correlations between individuals’ ages and ranked expression data were assessed using Pearson's product moment correlation coefficient.