FIG. 11.

Graphical summary of the main findings. Summary of time-dependent behavior, gene expression analysis, and structural analysis (protein and morphological) after blast. Trace fear abnormalities paralleled the time course of myelin structural changes after single and repeated blast, whereas spatial novelty preference deficits and structural change in the nodes of Ranvier and corpus callosum axons were evident only after repeated blast. CNPase, 2′,3-cyclic nucleotide-3-phosphodiesterase; Hapln2, hyaluronan and proteoglycan link protein 2; Mbp, myelin basic protein; Nefh, neurofilament heavy polypeptide. Color image is available online.