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. 2021 May 4;14(5):dmm047498. doi: 10.1242/dmm.047498

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© 2021. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — Differential expression analysis of Hnf1b^Sp2/+ mutant versus WT kidneys at different embryonic stages. (A) Venn diagram showing the overlap of genes differentially expressed from E14.5 to P0. (B) Gene ontology (GO) analysis of downregulated genes showing the top enriched terms (Table S4). (C) Venn diagrams show the overlap of differentially expressed genes of E17.5 Hnf1b^Sp2/+ and P0 Hnf4a knockout (KO) kidneys (Marable et al., 2020). Also indicated are HNF1 and HNF4 common target genes (red) and HNF1 targets (blue).