TABLE 3.

Cox Models Examining HIV Acquisition by PrEP Status

Variable	Incidence Rate Per 100 Person-Years (N)	Unadjusted Hazard Ratios (95% CI)	Adjusted Hazard Ratio (95% CI)
PrEP status
Not taking PrEP	1.86 (97)	Reference	Reference
Taking PrEP	0.17 (5)	0.20 (0.08 to 0.48)	0.21 (0.08 to 0.58)
Race/ethnicity
White	0.09 (64)	Reference	Reference
Black	0.12 (9)	1.38 (0.67 to 2.77)	1.21 (0.59 to 2.45)
Latinx	0.16 (30)	1.98 (1.29 to 3.04)	2.27 (1.38 to 3.74)
AI/AN	0 (0)	—	—
Asian	0.06 (5)	0.66 (0.27 to 1.64)	0.77 (0.30 to 1.94)
NH/PI	0.23 (5)	2.88 (1.16 to 7.16)	2.84 (1.13 to 7.12)
Other	0.13 (13)	1.50 (0.83 to 2.72)	0.77 (0.38 to 1.52)
Multiracial	0.14 (6)	1.65 (0.71 to 3.81)	1.35 (0.58 to 3.16)
Age
<20	0.22 (9)	2.35 (0.93 to 5.93)	1.85 (0.72 to 4.80)
20–29	0.09 (50)	0.97 (0.48 to 1.98)	0.80 (0.39 to 1.66)
30–39	0.07 (22)	0.70 (0.32 to 1.52)	0.61 (0.28 to 1.36)
40–49	0.10 (12)	0.93 (0.39 to 2.20)	0.88 (0.37 to 2.10)
50+	0.10 (9)	Reference	Reference
80
Gender
Cis or trans male	0.10 (102)	Reference	Reference
Trans female	—	—	—
NB/GQ/other	—	—	—
STI diagnosis
Syphilis	0.15 (20)	2.58 (1.37 to 4.85)	2.85 (1.49 to 5.44)
Gonorrhea	0.11 (62)	1.87 (1.12 to 3.14)	2.05 (1.22 to 3.46)
Chlamydia	0.05 (19)	Reference	Reference
Anal sex with men, past year
Yes		Reference	Reference
No		—	—
Missing		—	—
Methamphetamine use, past year
Yes		1.05 (0.99 to 1.02)	—
No		Reference	Reference
Year of HIV diagnosis
2014		Reference	Reference
2015		0.67 (0.42 to 1.06)	0.80 (0.48 to 1.23)
2016		0.36 (0.18 to 0.71)	0.38 (0.19 to 0.77)
2017		0.60 (0.30 to 1.19)	0.64 (0.32 to 1.30)
2018		—	—

AI/AN, American Indian/Alaska Native; Cis, cisgender; GQ, gender queer; NB, nonbinary; NH/PI, Native Hawaiian/Pacific Islander; STI, sexually transmitted infection; Trans, transgender.