Table 3.

Healthcare resource use whilst undiagnosed

Publication	ATTR-CM type	Time frame (years)	Healthcare professional visits	Primary care provider visits	Cardiologist visits	Other resource use
			% patients
Lousada 2019 [26]a	ATTRwt-CM (N = 91)	–	No. of different physicians seen 1: 16 2: 33 3: 16 4: 13  ≥ 5: 11	–	No. of different cardiologists seen 0: 0 1: 33 2: 38 3: 13 4: 2  ≥ 5: 3	–
	ATTRv-CM (N = 123)	–	1: 25 2: 14 3: 13 4: 14  ≥ 5: 23	–	0: 15 1: 37 2: 22 3: 7 4: 1  ≥ 5: 2	–
Kessler 2019 [23]	Mixed (i = 68)	–	≥ 3 HCPs seen: 69  ≥ 6 HCPs seen: 32	76.5 (median of 3 visits)	75% (median of 2 visits)	–
Lane 2019 [3]	Mixed (N not reported)	3	–	–	–	Hospital stays (n): 17 (median) Inpatient hospitalizations (n): 3 (median)
Lousada 2017 [24]a	Mixed (N = 139)	–	≥ 3 visits: 44  ≥ 5 visits: 17	–	–	–

“–” Not reported by studies

ATTR-CM transthyretin amyloid cardiomyopathy, ATTRv-CM hereditary transthyretin amyloid cardiomyopathy, ATTRwt-CM wild-type transthyretin amyloid cardiomyopathy, HCP healthcare professional

^aPublications belong to the same parent study: Amyloidosis Research Consortium, the Amyloidosis Foundation and Amyloidosis Support Groups