Figure 5.
Tanshinone IIA (TIIA)+ cyclosporine A (CsA) preserved lung mitochondrial biogenesis and dynamics in renal renal ischemia-reperfusion (IR)-induced lung injury. The expression of PGC-1α, Nrf1, and Tfam in mRNA (A) and protein (B) levels. The expression of Mfn1, Mfn2, and Drp1 in mRNA level. *p < 0.05 vs. sham group, #p < 0.05 vs. IR (obese) group, ▵p < 0.05 vs. TIIA group, ▴p < 0.05 vs. CsA group.