Table 2.
Laboratory findings between pregnant and non-pregnant COVID-19 patients and healthy pregnant women.
| Laboratory Findings | COVID-19 Non-pregnant (n = 80) | COVID-19 Pregnant (n = 20) | Healthy Pregnant (n = 10) | P value |
|---|---|---|---|---|
| Age, years | 34.00 (30.00–39.75) | 33.00 (30.00–34.75) | 34.00 (29.75–34.25) | 0.426 |
| WBC, *10^9/L | 6.21 (4.62–7.18) a | 7.85 (5.94–9.14) b | 8.29 (7.44–10.59) b | <0.001 |
| Lymphocytes, *10^9/L | 1.77 (1.30–2.23) a | 1.33 (0.94–1.60) b | 1.35 (1.20–1.80) ab | 0.004 |
| Lymphocytes, % | 0.31 (0.25–0.38) a | 0.19 (0.13–0.22) b | 0.17 (0.12–0.25) b | <0.001 |
| Monocytes, *10^9/L | 0.46 (0.35–0.56) | 0.48 (0.34–0.63) | 0.50 (0.41–0.63) | 0.559 |
| Monocytes, % | 0.08 (0.06–0.09) a | 0.06 (0.05–0.08) b | 0.06 (0.04–0.10) ab | 0.016 |
| Neutrophils, *10^9/L | 3.43 (2.38–4.31) a | 5.60 (4.32–7.54) b | 6.08 (4.93–9.05) b | <0.001 |
| Neutrophils, % | 0.58 (0.51–0.64) a | 0.75 (0.70–0.83) b | 0.76 (0.65–0.83) b | <0.001 |
| Eosinophil, *10^9/L | 0.07 (0.04–0.13) a | 0.02 (0.00–0.05) b | 0.03 (0.01–0.08) ab | <0.001 |
| Eosinophil, % | 0.01 (0.006–0.02) a | 0.0022 (0.00–0.0071) b | 0.0039 (0.001–0.0092) b | <0.001 |
| Basophil, *10^9/L | 0.02 (0.01–0.03) | 0.01 (0.01–0.02) | 0.02 (0.01–0.03) | 0.185 |
| Basophil, % | 0.0031 (0.0021–0.0048) a | 0.0017 (0.0011–0.0033) b | 0.0023 (0.0011–0.0029) ab | 0.005 |
| RBC, *10^9/L | 4.18 (3.98–4.39) a | 3.74 (3.46–4.16) b | 3.73 (3.60–3.96) b | <0.001 |
| Hematocrit, % | 36.90 (35.20–38.70) a | 33.25 (31.53–35.70) b | 34.10 (30.78–35.60) b | <0.001 |
| Hemoglobin, g/L | 126.00 (120.00–132.00) a | 112.50 (101.50–125.75) b | 117.5 (97.75–122.25) b | <0.001 |
| Platelet, *10^9/L | 231.00 (200.00–288.75) | 196.50 (141.50–246.50) | 224.50 (160.00–266.75) | 0.042 |
| ALT, U/L | 12.00 (9.00–30.00) a | 12.00 (8.25–19.00) ab | 8.00 (6.75–12.25) b | 0.036 |
| AST, U/L | 17.00 (14.00–23.00) | 17.00 (14.25–22.00) | 17.5 (14.5–20.0) | 0.866 |
| Total Bilirubin, mmol/L | 6.60 (4.40–8.45) | 6.15 (5.03–8.08) | 5.70 (2.58–8.03) | 0.342 |
| Direct Bilirubin, mmol/L | 2.80 (2.20–3.60) | 3.15 (2.48–3.88) | 2.55 (1.60–3.20) | 0.144 |
| Indirect Bilirubin, mmol/L | 3.80 (2.33–4.98) | 2.85 (1.83–4.03) | 2.90 (0.98–5.20) | 0.065 |
| Serum Creatinine, umol/L | 55.00 (50.00–62.00) a | 48.00 (42.25–53.75) b | 44.50 (36.25–53.00) b | <0.001 |
| Blood Urea, umol/L | 3.40 (2.70–4.30) a | 2.88 (2.18–3.60) b | 3.20 (2.54–3.73) ab | 0.046 |
| Lactic dehydrogenase, U/L | 180.00 (149.00–220.00) | 192.00 (168.50–247.50) | 183.50 (150.25–215.00) | 0.365 |
| Alkaline phosphatase, U/L | 50.00 (42.00–59.00) a | 107.50 (75.50–122.25) b | 114.0 (79.25–151.75) b | <0.001 |
| Prothrombin time, s | 13.50 (13.10–13.50) a | 13.10 (12.73–13.48) b | 12.9 (12.7–13.15) b | 0.001 |
| APTT, s | 39.70 (37.35–41.58) a | 38.50 (33.20–40.05) ab | 33.90 (30.55–36.60) b | 0.001 |
| D-Dimer, ug/ml | 0.26 (0.22–0.55) a | 1.31 (0.72–1.71) b | 1.16 (0.85–1.98) b | <0.001 |
| Hs-CRP, mg/L | 1.30 (0.45–8.05) a | 15.90 (2.58–36.35) b | 2.6 (1.2–20.8) ab | 0.001 |
| Procalcitonin, ng/ml | 0.05 (0.04–0.06) | 0.06 (0.38–0.10) | 0.07 (0.04–0.58) | 0.328 |
The data was shown as median and interquartile range.
WBC, White blood cell; RBC, Red blood cell; ALT, Alanine aminotransferase; AST, Aspartate aminotransferase; APTT, Activated partial thromboplastin time; Hs-CRP, High sensitivity C-reactive protein; TNF, Tumor necrosis factor.
*represents multiplication sign.
a, b, abindicated statistical differences between groups labeled with different letters and no significance between groups labeled with the same letter.
Bold P values indicated statistical differences.