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. 2021 May 3;11:663771. doi: 10.3389/fonc.2021.663771

Table 3.

Principal pathways of Inflammation Cluster for the subset B.

Inflammation Upregulated genes Downregulated genes
IL-18 signaling pathway NCF2, CCL4, PLOD3, BID, HCAR2, FN1, PTGS2, TGM2, ULBP2 FOXN3, KLF2, PRKCB, CCL19, DES, ACTA2, NR0B2, SPON1
Chemokine signaling pathway CXCR2, CCL4 CCL19, CCL11, CXCL14, VAV3, PRKCB, PRKACB, AKT3
Spinal Cord Injury E2F1, RTN4R, LILRB3, PTGS2, GJA1 SLIT2, SLIT3, RGMA, VIM
Prostaglandin Synthesis and Regulation PTGS2 PTGFR, PTGER1, HPGD, HPGDS, AKR1C3, AKR1C1, AKR1C2
B Cell Receptor Signaling Pathway   CD79B, CD79A, BLNK, BLK, CR2
T-Cell antigen Receptor (TCR) Signaling Pathway RIPK2 GRAP2, VAV3, VIM
IL1 and megakaryocytes in obesity TIMP1, S100A9 SELENBP1, FCER1A
TGF-beta Receptor Signaling BAMBI, SERPINE1 BMP4
Interferon type I signaling pathways SOCS3 PDCD4, PTPRC
Inflammatory Response Pathway FN1, LAMA5 CD40LG