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Potency of DNA-demethylating agents at optimal doses for induction of Treg cells in vitro
| %Treg cells | Total no. of Treg cells | MFI of Foxp3 | MFI of CD25 | |
| Decitabine (1 μM) | 30 ± 11 | 5,953 ± 2,795 | 2,897 ± 48 | 3,958 ± 535 |
| Psammaplin A (1 μM) | 10 ± 4 | 1,697 ± 311 | 1,369 ± 32 | 2,129 ± 394 |
| Procainamide (200 μM) | 1 ± 1 | 398 ± 303 | 505 ± 83 | 1,895 ± 118 |
| Zebularine (100 μM) | 23 ± 4 | 2,920 ± 851 | 1,939 ± 67 | 3,295 ± 198 |
Data are expressed as means ± SD.
