Table 2.
Baseline Characteristics of Cases of Early Colorectal Neoplasm and Controls in the Training and Validation Datasets
| Training Data | P value | Validation Data | P value | |||
|---|---|---|---|---|---|---|
| Cases (n = 1292) | Controls (n = 6460) | Cases (n = 554) | Controls (n = 2770) | |||
| Age,year,mean (SD) | 60.90 (5.99) | 60.16 (6.40) | 0.00 | 61.1 (5.99) | 59.95 (6.47) | 0.00 |
| Sex, n(%) | 0.00 | 0.00 | ||||
| Male | 799 (61.84) | 3022 (46.78) | 345 (62.27) | 1267 (45.74) | ||
| Female | 493 (38.16) | 3438 (53.20) | 209 (37.73) | 1503 (54.26) | ||
| BMI, kg/m,2 mean (SD) | 24.19 (3.09) | 23.81 (3.02) | 0.00 | 24.20 (3.19) | 23.84 (2.95) | 0.02 |
| 18.5 ≤ BMI < 24 | 485 (47.41) | 2391 (51.79) | 204 (48.11) | 987 (50.62) | ||
| BMI < 18.5 | 24 (2.35) | 122 (2.64) | 6 (1.42) | 54 (2.77) | ||
| 24 ≤ BMI < 28 | 397 (38.81) | 1731 (37.49) | 175 (41.27) | 755 (38.72) | ||
| BMI ≥ 28 | 117 (11.44) | 373 (8.08) | 39 (9.20) | 154 (7.90) | ||
| Family history, n (%) | 0.00 | 0.00 | ||||
| Yes | 89 (6.92) | 169 (2.62) | 51 (9.24) | 63 (2.28) | ||
| No | 1197 (93.08) | 6270 (97.38) | 501 (90.76) | 2698 (97.72) | ||
| Smoking, n (%) | 0.00 | 0.00 | ||||
| No | 708 (54.80) | 4408 (68.24) | 310 (55.96) | 1920 (69.44) | ||
| Current/ever | 574 (45.20) | 2052 (31.76) | 244 (44.04) | 845 (30.56) | ||
| Alcohol, n (%) | 0.00 | 0.00 | ||||
| No | 893 (69.12) | 5161 (79.94) | 384 (69.44) | 2210 (80.01) | ||
| Current/ever | 399 (30.88) | 1295 (20.06) | 169 (30.56) | 552 (19.99) | ||
| Intake of fatty fooda, n (%) | 0.05 | 0.96 | ||||
| Occasional | 964 (75.85) | 4941 (78.38) | 417 (77.51) | 2091 (77.59) | ||
| Regular | 307 (24.15) | 1363 (21.62) | 121 (22.49) | 604 (22.41) | ||
| Intake of fried fooda, n (%) | 0.02 | 0.31 | ||||
| Occasional | 1135 (91.38) | 5754 (93.27) | 486 (93.82) | 2455 (92.50) | ||
| Regular | 107 (8.62) | 415 (6.73) | 32 (6.18) | 199 (7.50) | ||
| Intake of pickled fooda, n (%) | 0.01 | 0.07 | ||||
| Occasional | 926 (72.91) | 4790 (76.26) | 392 (73.27) | 2061 (76.90) | ||
| Regular | 344 (27.09) | 1491 (23.74) | 143 (26.73) | 619 (23.10) | ||
| Moderate-to-intensity physical activityb, n (%) | 0.00 | 0.18 | ||||
| Never | 225 (21.99) | 806(17.31) | 90 (21.23) | 362 (18.43) | ||
| Regular | 798 (78.01) | 3849(82.69) | 334 (78.77) | 1602 (81.57) | ||
Notes: aThe dietary factors including the intake of fatty meat, fried food, and pickled food were categorized as occasional (<3 days per week) or regular (3–7 days per week). bModerate-to-intensity physical activity was classified as never or regular (at least 1 day per week).
Abbreviations: SD, standard deviation; BMI, body mass index.