FIGURE 6.

Transplantation of hybrid 3D cell spheroids improves renal function in mice with hypertensive nephropathy. (a) The blood urea nitrogen (BUN) and urine albumin‐creatinine ratio (UACR) of experimental animals that received saline (n = 3) or PME spheroids (n = 6) are normalized to preoperative values. (b) Number of podocytes per glomerulus of the kidney retrieved from the experimental animals. (c) Fluorescence images showing the engraftment of transplanted large T antigen‐positive podocytes. Inset shows a magnified view. Scale bars, 10 μm. All p values were calculated using two‐tailed Student's t‐test. **p < 0.01; ****p < 0.001; ns, not significant