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Schematic illustration of mode of action of choline and geranic acid (CAGE) for rosacea. (a) Synthetic scheme of CAGE/CGB400 gel, deep eutectic mixture. (b) CGB400 upon topical application, extracts lipid from the lipid bilayer and penetrates deep into the skin layers. (c) CAGE neutralizes pathogens, modulates TLR2 signaling, and inhibits KLK5 and thus generation of pro‐inflammatory peptides
