Table 2.

WU cohort: Hierarchical linear regressions with log-transformed lesion volume, edge density load, and participation coefficient load predicting post-lesion g scores

	Step and Variable		95% CI for b
		b	Lower bound	Upper bound	β	t	p	Df	R2	ΔR2	Sig. ΔF	AIC
Model 1	Step 1
	Total Lesion Volume (log mm3)	−0.228	−0.335	−0.120	−0.386	−4.189	<0.001	100	0.141	0.149	<0.001	−13.498
	Step 2
	Total Lesion Volume (log mm3)	−0.145	−0.311	0.022	−0.246	−1.726	0.087	98	0.169	0.044	0.074	−14.906
	Edge Density Load	−0.421	−0.788	−0.053	−0.421	−2.272	0.025	98	0.169	0.044	0.074	−14.906
	Participation Coefficient Load	0.231	−0.137	0.599	0.231	1.244	0.217	98	0.169	0.044	0.074	−14.906
Model 2	Step 1
	Total Lesion Volume (log mm3)	−0.221	−0.338	−0.104	−0.357	−3.742	<0.001	96	0.118	0.127	<0.001	−10.100
	Step 2
	Total Lesion Volume (log mm3)	−0.191	−0.369	−0.012	−0.309	−2.122	0.036	95	0.111	0.002	0.661	−8.300
	Participation Coefficient Load	−0.063	−0.350	0.223	−0.064	−0.441	0.661	95	0.111	0.002	0.661	−8.300
Model 3	Step 1
	Total Lesion Volume (log mm3)	−0.228	−0.335	−0.120	−0.386	−4.189	<0.001	100	0.141	0.149	<0.001	−13.498
	Step 2
	Total Lesion Volume (log mm3)	−0.112	−0.271	0.046	−0.191	−1.406	0.163	99	0.164	0.031	0.055	−15.308
	Edge Density Load	−0.263	−0.533	0.006	−0.263	−1.941	0.055	99	0.164	0.031	0.055	−15.308

Note: R² represents adjusted R². Four patients had lesions that did not intersect with the participation coefficient map and were thus excluded from Model 2 (n = 98).