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. 2021 May 3;118(19):e2018784118. doi: 10.1073/pnas.2018784118

Table 3.

Iowa cohort: Hierarchical linear regressions with log-transformed lesion volume, eigenvector centrality load, gateway centrality load, subgraph centrality load, weighted degree, within-module degree, and community density predicting post-lesion g scores

Step and Variable 95% CI for b
B Lower bound Upper bound β t p df R2 ΔR2 Sig. ΔF AIC
Step 1
  Total Lesion Volume (log mm3) −0.119 −0.179 −0.059 −0.193 −3.926 <0.001 400 0.035 0.037 <0.001 −80.006
Step 2
  Total Lesion Volume (log mm3) −0.044 −0.116 0.027 −0.072 −1.219 0.224 399 0.062 0.030 <0.001 −90.525
  Eigenvector Centrality Load −0.193 −0.300 −0.086 −0.210 −3.553 <0.001 399 0.062 0.030 <0.001 −90.525
Step 1
  Total Lesion Volume (log mm3) −0.119 −0.179 −0.059 −0.193 −3.926 <0.001 400 0.035 0.037 <0.001 −80.006
Step 2
  Total Lesion Volume (log mm3) −0.017 −0.102 0.067 −0.028 −0.400 0.689 399 0.058 0.025 0.001 −88.775
  Gateway Centrality Load −0.211 −0.337 −0.085 −0.229 −3.291 0.001 399 0.058 0.025 0.001 −88.775
Step 1
  Total Lesion Volume (log mm3) −0.119 −0.179 −0.059 −0.193 −3.926 <0.001 400 0.035 0.037 <0.001 −80.006
Step 2
  Total Lesion Volume (log mm3) −0.040 −0.112 0.031 −0.066 −1.107 0.269 399 0.064 0.032 <0.001 −91.614
  Subgraph Centrality Load −0.202 −0.309 −0.095 −0.220 −3.707 <0.001 399 0.064 0.032 <0.001 −91.614
Step 1
  Total Lesion Volume (log mm3) −0.119 −0.179 −0.059 −0.193 −3.926 <0.001 400 0.035 0.037 <0.001 −80.006
Step 2
  Total Lesion Volume (log mm3) −0.010 −0.094 0.073 −0.017 −0.241 0.810 399 0.063 0.030 <0.001 −90.925
  Weighted Degree Load −0.228 −0.352 −0.104 −0.248 −3.610 <0.001 399 0.063 0.030 <0.001 −90.925
Step 1
  Total Lesion Volume (log mm3) −0.119 −0.179 −0.059 −0.193 −3.926 <0.001 400 0.035 0.037 <0.001 −80.006
Step 2
  Total Lesion Volume (log mm3) −0.019 −0.102 0.064 −0.030 −0.444 0.657 399 0.059 0.027 0.001 −89.240
  Within-Module Degree Load −0.211 −0.335 −0.088 −0.230 −3.363 0.001 399 0.059 0.027 0.001 −89.240
Step 1
  Total Lesion Volume (log mm3) −0.118 −0.178 −0.058 −0.191 −3.867 <0.001 395 0.034 0.036 <0.001 −80.006
Step 2
  Total Lesion Volume (log mm3) −0.023 −0.108 0.061 −0.037 −0.537 0.592 393 0.074 0.044 <0.001 −86.189
  Community Density Load −0.202 −0.330 −0.073 −0.215 −3.085 0.002 393 0.074 0.044 <0.001 −86.189

Note: R2 represents adjusted R2. AIC = Akaike Information Criterion.