DENV-2 inhibitory properties of harmol and 9-methylharmine.
Compd | DENV-2 inhibitory activity | DENV-1 | DENV-3 | DENV-4 | ||
---|---|---|---|---|---|---|
CC50 (μM) | EC50 (μM) | SI | EC50 (μM) | |||
81 | 203.3 | 3.3 | 61.3 | 10.1 | 7.7 | 21.1 |
82 | 178.6 | 3.2 | 56.2 | 49.5 | 33.7 | 16.3 |
Compd | DENV-2 inhibitory activity | DENV-1 | DENV-3 | DENV-4 | ||
---|---|---|---|---|---|---|
CC50 (μM) | EC50 (μM) | SI | EC50 (μM) | |||
81 | 203.3 | 3.3 | 61.3 | 10.1 | 7.7 | 21.1 |
82 | 178.6 | 3.2 | 56.2 | 49.5 | 33.7 | 16.3 |