Anti-HCV properties of isomers of compound 20 and 21.
| Compd | Anti-HCV activity | CC50, μM | SI |
|---|---|---|---|
| EC50, μM | |||
| (R) 20 | 0.72 | >50 | >69.44 |
| (S) 20 | 7.12 | 34.57 | 4.86 |
| (R) 21 | 0.74 | 31.06 | 41.97 |
| (S) 21 | 5.87 | 23.31 | 3.97 |
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