Anti-HIV-1 NL4-3 and anti-HIV-1 IIIB inhibitory properties of IASs.
| Compd | HIV-1 NL4-3 | HIV-1 IIIB | ||
|---|---|---|---|---|
| CC50 (nM) | EC50 (nM) | SI | EC50 (nM) | |
| 57 | 23 769 | 0.22 | 89 643 | 17 |
| 58 | 30 216 | 0.2 | 151 078 | 4.1 |
| 59 | 54 589 | 0.6 | 90 981 | 3.2 |
| 60 | 25 350 | 0.62 | 40 887 | 4.1 |
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