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. 2021 May 4;13(3):1094–1101. doi: 10.1111/os.12990

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© 2021 The Authors. Orthopaedic Surgery published by Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig 2 — S100A6 affects the inflammation reaction of osteoarthritis. (A) The quantitative PCR assays showed the expression of IL‐6 and MMP‐13 were increased in in OA model. The values were decreased after the treatment of AdS100A6 and increased after the treatment of AdsiS100A6. (B, C) Western blot assays exhibited the expression of IL‐6 and MMP‐13 was increased in OA model. And the expression levels were down‐regulated by the treatment of AdS100A6 and up‐regulated by the treatment of AdsiS100A6. Results are presented as mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001.