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. 2021 Apr 12;40(10):e104847. doi: 10.15252/embj.2020104847

Figure EV5. MRX complex suppresses BIR in allelic recombination.

Figure EV5

  1. Percentage of BIR and chromosome loss in WT and mre11∆ cells in allelic recombination. Chi‐square test is used to determine the P‐value, number of colonies tested per mutant is indicated in Appendix Table S1.
  2. Schematic of allelic assay with a TRP1 probe (yellow box) used for Southern blot analysis. Ethidium bromide gel (top) and Southern blot with TRP1 probe (bottom) showing chromosome III of haploid parental strains, diploid, and BIR products of WT (left) and mre11∆ cells (right). “*” depicts gross chromosomal arrangement event.

Data information: *P‐value 0.01 to 0.05, significant; **P‐value 0.001 to 0.01, very significant; ***P‐value 0.0001 to 0.001, extremely significant; ****P < 0.0001, extremely significant; P ≥ 0.05, not significant (ns).