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. 2021 May 6;24(1):498. doi: 10.3892/mmr.2021.12137

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Copyright: © Jiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Expression levels and ROC curves of screened miRs in serum EVs. Reverse transcription-quantitative PCR was used to determine mRNA expression levels of (A) miR-122-5p, (B) miR-129-5p, (C) miR-135a-3p and (D) miR-504-3p in serum EVs and (E) serum ALT levels in patients with NAFLD (n=50) and control subjects (n=50). ROC curves and AUC for serum EV-derived (F) miR-122-5p, (G) miR-135a-3p, (H) miR-129-5p, (I) miR-504-3p and (J) ALT levels in patients with NAFLD. Data are presented as the mean ± SD. ***P<0.001, ****P<0.0001. ROC, receiver operator characteristic; miR, microRNA, EVs, extracellular vesicles; AUC, area under the curve; ALT, alanine aminotransferase; NAFLD, non-alcoholic fatty liver disease.

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