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Genotype and allele frequencies of the TMPRSS2 p.Val160Met polymorphism according to COVID-19 severity
| Asymptomatic (N=21) | Mild (N=12) | Moderate (N=32) | Severe (N=30) | Chi-square test | |||||
|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | ||
| Genotype (amino acids) | |||||||||
| CC (Val/Val) | 8 | 38.1 | 4 | 33.3 | 17 | 53.1 | 13 | 43.4 | χ2= 3.11 |
| CT (Val/Met) | 7 | 33.3 | 5 | 41.7 | 11 | 34.4 | 10 | 33.3 | P=0.79 |
| TT (Met/Met) | 6 | 28.6 | 3 | 25 | 4 | 12.5 | 7 | 23.3 | |
| Allele | |||||||||
| C Allele | 23 | 54.8 | 13 | 54.2 | 45 | 70.3 | 36 | 60 | χ2= 3.51 |
| T Allele | 19 | 45.2 | 11 | 45.8 | 19 | 29.7 | 24 | 40 | P=0.32 |
