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. 2021 May 17;22:180. doi: 10.1186/s12882-021-02374-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Area under the curves (AUCs) of receiving operator characteristics for the absolute counts of CD19 + CD25 + Bregs and Tregs, serum TGF-ß1, and serum IL-10 as possible identifiers of eGFR ≥ 30 ml/min. The optimal cutoff values were obtained through analysis of coordinate points of ROC curve. The AUC of CD19 + CD25 + Bregs as well as serum TGFβ1 showed statistical significance (AUC = 0.66, p = 0.018, AUC = 0.68, p = 0.006, respectively). AUC values of Treg absolute count as well as serum IL-10 were not significantly increased (AUC = 0.52, p = 0.7; AUC = 0.54, p = 0.5, respectively)