Table 2.

Comparison of the absolute and relative counts of CD19+ B cell subsets and CD4 + CD25 + CD127-Foxp3+ Tregs in healthy controls (HC), end-stage renal disease patients (ESRD) and renal transplant recipients (Tx)

	HC (n = 31)	ESRD (n = 18)	Tx (n = 90)	P
CD19+/μl	228 (159–277)	56 (27–117)	74 (40–155)	0.009
%CD19+	13 (9–16)	5.5 (4–9)	9 (4–17)	< 0.001
CD19 + CD25+/μl	3.3 (1.8–5.2)	0.3 (0.06–0.8)	0.2 (0.04–0.47)	< 0.001
%CD19 + CD25+	0.2 (0.1–0.2)	0.03 (0.01–0.1)	0.02 (0.00–0.05)	< 0.001
CD19 + CD25 + Foxp3+/μl	0.16 (0.0–0.4)	0.0 (0.0–0.07)	0.0 (0.0–0.05)	< 0.001
%CD19 + CD25 + Foxp3+	0.01 (0.00–0.02)	0.00 (0.00–0.01)	0.00 (0.00–0.00)	< 0.001
CD19 + CD25 + Foxp3−/μl	3 (1.1–4)	0.23 (0.00–0.68)	0.2 (0.0–0.45)	< 0.001
%CD19 + CD25 + Foxp3-	0.17 (0.1–0.2)	0.02 (0.00–0.07)	0.02 (0.00–0.04)	< 0.001
Treg/μl	8 (4–16	4 (2–11)	2 (0.5–6)	< 0.001
%Treg	0.5 (0.2–0.7)	0.5 (0.3–1.2)	0.2 (0.1–0.5)	0.002

All values are expressed as median and Interquartile range % represent the proportion of cells to all lymphocytes (CD45+ cells)