Table 3.

The Relationship Between the Baseline at Enrollment and the Antibiotic Resistance of Pylori Isolates by NGS

Factors	N	Resistant Genotype of Clarithromycin			Resistant Genotype of Levofloxacin
		Mutation Rate (%)	Univariate Analysis P value	Multivariate Analysis P value	Mutation Rate (%)	Univariate Analysis P value	Multivariate Analysis P value
Gender			0.260	0.400		0.359	0.334
Female	256	41.0			28.1
Male	233	36.1			24.5
Age			0.083	0.036		0.009	0.040
<35 YO	187	44.4			18.7
35–50YO	195	36.9			30.3
>50YO	107	31.8			32.7
Clinical diagnosis			0.138	0.220		0.849	0.868
PUD	63	30.2			25.4
NUD	426	39.9			36.5
Chronic atrophic gastritis			0.241	0.341		0.001	0.044
CAG	81	44.4			40.7
Non-CAG	408	37.5			23.5
Intestinal metaplasia			0.411	0.666		0.028	0.879
IM	117	41.9			34.2
Non-IM	372	37.6			23.9
Lymphoid aggregates			0.333	0.304		0.430	0.590
Yes	266	40.6			20.7
No	223	36.3			33.2

Abbreviations: PUD, peptic ulcer disease; NUD, non-ulcerative dyspepsia; CAG, chronic atrophic gastritis; IM, intestinal metaplasia.