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. 2021 May 11;14:467–483. doi: 10.2147/CCID.S301117

Table 4.

Overview of the Different Hyaluronic Acid (HA) Fillers Used in Tear Trough Deformity Treatment and Their Main Characteristics

VYC-25L* VYC-20L* VYC-17.5L* VYC-15L* VYC-12L*
Indication Restore and create volume of the face. Facial volume restoration. Treatment of deep skin depressions, face contouring and volume restoration to correct facial structural defects, contour deformities volume loss in the lips, cheeks, chin, lower face. Treatment of fine lines and medium-sized skin depressions, enhancement and pouting of the lips to correct structural defects, contour deformities and volume loss. Treatment of superficial cutaneous depressions such as fine lines and for improvement of skin quality attributes such as hydration and elasticity.
Concentration of HA 25 mg/mL 20 mg/mL 17.5 mg/mL 15 mg/mL 12 mg/mL
HA molecular weight Low & high Low & high Low & high Low & high Low & high
Duration Up to18 months Up 2 years Up to 18 months Up 1 year Up to 9 months

Note: *With lidocaine.

Abbreviations: VYC-25L, Volux® (Allergan plc, Dublin, Ireland); VYC-20L, Voluma® (Allergan plc, Dublin, Ireland); VYC-17.5L, Volif® (Allergan plc, Dublin, Ireland); Volbella® (Allergan plc, Dublin, Ireland); VYC-12L, Volite® (Allergan plc, Dublin, Ireland); HA, hyaluronic acid.