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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Nat Med. 2021 Apr 1;27(5):785–789. doi: 10.1038/s41591-021-01297-7

Extended Data Fig. 6. Lack of discernable changes in RPE melanization.

Extended Data Fig. 6

a, Near-infrared excited autofluorescence (NIRAF) images of the macular region in the untreated and treated eyes showing an elliptical region of preserved RPE melanization in both eyes qualitatively unchanged through month 15. b, c Normalized NIRAF intensity profiles as a function of retinal eccentricity in both horizontal (b) and vertical meridian (c). Month 12 (red traces) and baseline visit (black traces) are highlighted to demonstrate lack of change. Vertical dashed black line represents the fovea. d, Foveal NIRAF intensity used for normalization of the traces in panels b and c. Symbols are individual data points.