Fig. 1.

Adaptive pooled testing strategies: (A) Dorfman Pooling: Population is divided into two pools of optimum size 8 and tested. The positively tested pool is then deconvoluted to identify the individual infected sample. (B) Column and row pooling: On a 96-well plate, rows and columns are pooled separately. The negative rows and columns are excluded. The individuals from positive rows and columns are then tested individually. In the above illustration, 5 positive samples are identified with 45 tests, compared to 96 tests if tested individually. (C) Household grouping: Pools are formed from each household in a locality and tested. Positive groups undergo individual testing.