Snelling 1983.

Study characteristics
Methods	Randomised controlled trial Duration: 7–10 days, but 48 hours if participants were asymptomatic and had negative blood cultures Date: NA Location: Liverpool Maternity Hospital, Liverpool, UK
Participants	55 neonates with suspected serious infection within 48 hours of birth Gender (boys/girls): NA Age: < 48 hours at randomisation Inclusion criteria: < 48 hours after birth with confirmed sepsis, signs highly suggestive of sepsis or who were at particular high risk of developing sepsis Exclusion criteria: not described
Interventions	Intervention 1: ceftazidime 50 mg/kg 12 hourly (n = 31) Intervention 2: gentamicin 3 mg/kg + benzylpenicillin 15 mg/kg 12 hourly (n = 24)
Outcomes	Mortality Treatment failure Bacteriological resistance Follow‐up Not reported
Notes	Not possible to contact the authors.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described.
Allocation concealment (selection bias)	Unclear risk	Not described.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Blinding of intervention and outcome measurements not reported.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Blinding of intervention and outcome measurements not reported.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No dropouts.
Selective reporting (reporting bias)	Low risk	Reported mortality and serious adverse events.
Other bias	Low risk	No other biases were identified.