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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Inflamm Res. 2021 Feb 10;70(3):359–373. doi: 10.1007/s00011-021-01443-4

Fig. 10. Histopathology analysis of lung tissue in chronic model.

Fig. 10

Balb/c mice were instilled with either DM-only, MWCNT, or SiO2 once a week at weeks 0, 1, 2, 3 while on the normal mouse chow and at week 4 were put on a control or 1% DHA diet for 12 weeks. (a) Pathology was scored blinded by two observers; data presented as median ± SEM. (b) Airway thickness was measured blinded; data presented as mean ± SEM. (c) Representative images (10x) of Masson’s trichrome-stained lung airway sections. n=3; *P<0.05, **P<0.01, ***P<0.001 compared to DM, + compared to different diet within the same exposure group. Arrows indicate particle encapsulation, arrow head indicates increased lung airway thickness, and blue staining indicates collagen deposition